Quam A, Biernacki K, Ross TJ, Salmeron BJ, Janes AC (In Press) Childhood trauma and emotional awareness impact neural correlates of chronic nicotine use. JAMA-Open


Wanger TJ, De Moura FB, Ashare R, Loughead J, Lukas S, Lerman C, Janes AC. ( 2023). Brain and cortisol responses to smoking cues are linked in tobacco smoking individuals. Addiction Biology

Biernacki K, Molokotos E, Han C, Dillon D, Leventhal AM, Janes AC (2023). Enhanced decision-making in nicotine dependent individuals who abstain: A computational analysis using hierarchical drift diffusion modeling. Drug and Alcohol Dependence.

Wanger T, Janes AC, Frederick BF (2023). Spatial variation of changes in test-retest reliability of functional connectivity after global signal regression: the effect of considering hemodynamic delay. Human Brain Mapping


Murray L, Welsh JC, Johnson CG, Kaiser RH, Farchione TJ, Janes AC (2022). Alcohol and non-alcohol-related interference: An fMRI study of treatment-seeking adults with alcohol use disorder. Drug and Alcohol Dependence

Campbell AS, Needham BD, Meyer CR, Tan J, Contrad M, Preston GP, Bolognani F, Rao SG, Heussler H, Griffith R, Guastella AJ, Janes AC, Frederick B, Donabedian DH, Mazmania SK (2022) Safety and target-engagement of an oral small molecule sequesterant in adolescents with Autism Spectrum Disorder: an open-label phase 1b/2a3 trial. Nature Medicine

Ward HB, Beerman A, Nawaz U, Halko MA, Janes AC, Moran LV, Brady RO. Evidence for schizophrenia-specific pathophysiology of nicotine dependence. (2022). Frontiers in Psychiatry-Schizophrenia.

Ekhtiari H, Zare-Bidoky M,Sangchooli A, Janes AC et al (2022) A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus. Nature Protocols.


Centanni SW, Janes AC, Haggerty DL, Atwood B, Hopf FW (2021). Better living through understanding the insula: Why subregions can make all the difference. Neuropharmacology.

Wang KS, Brown K, Frederick BB, Moran LV, Olson D, Pizzagalli DA, Kaiser RH, Janes AC (2021). Nicotine acutely alters temporal properties of resting brain states. Drug and Alcohol Dependence

Franklin TR., Jagannathan K, Spilka NH., Keyser H., Rao H., Ely AV., Janes AC., Wetherill RR. (2021). Smoking-induced craving relief relates to increased DLPFC-striatal coupling in nicotine-dependent women. Drug and Alcohol Dependence

Murray L. ,Maurer JM., Peechatka AL., Frederick BB., Kaiser RH.,  Janes AC (2021). Sex Differences in Functional Network Dynamics Observed Using Coactivation Pattern AnalysisCognitive Neuroscience.   


Wang KS, Kaiser RH, Peechatka, AL, Frederick BB, Janes AC (2020) Temporal dynamics of large-scale networks predict neural cue reactivity and cue-induced craving. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

Janes AC (2020) Is it worth the effort? Science. 1300-1301.

Janes AC, Krantz NL, Nickerson LD, Frederic BB, Lukas SE (2020) Craving and cue-reactivity in nicotine-dependent tobacco smokers is associated with different insula networks. Biological Psychiatry: Cogn Neurosci Neuroimaging. 67-83.

Janes AC, Peechatka AL, Frederick BB, Kaiser RH (2020) Dynamic functioning of transient resting-state co-activation networks in the human connectome project. Human Brain Mapping

Copersino ML, Patel R, Price JS, Visser KF, Vitaliano G, Plitman E, Lukas SE, Weiss RD, Janes AC, Chakravarty MM (2020) Interactive effects of age and recent substance use on stratal shape morphology at substance use disorder treatment entry. Drug and Alcohol Dependence

McHugh RK, Janes AC, Griffin ML, Taghian N, Greenfield SF, Weiss RD (2020) Clinical correlates of smoking status in men and women with opiate use disorder. Substance Use and Misuse

Allenby C, Falcone M, Wileyto EP, Cao W, Bernardo L, Ashare RL, Janes AC., Loughead J, Lerman C (2020) Neural cue reactivity during acute withdrawal predicts short-term smoking relapse. Addiction Biology

Molokotos E, Peechatka AL, Wang KS, Pizzagalli DA, Janes AC (2020) Caudate reactivity to smoking cues is associated with increased responding to monetary reward in nicotine-dependent individuals. Drug and Alcohol Dependence.

Wang KS, Zegel M, Molokotos E, Moran LV, Olson DP, Pizzagalli DA, Janes AC (2020) The acute effects of nicotine on corticostriatal responses to distinct phases of reward processing. Neuropsychopharmacology.


Peechatka A, Molokotos E, Zegel M, Lukas S, Janes AC(2019) A preliminary examination of nicotine-free electronic cigarette use during cessation from combustible cigarettes. Frontiers in Psychiatry. 2019.00559

Janes AC, Datko M, Roy A, Barton B, Drucker S, Neal C, Ohasi K, Benoit H, Lutterveld R, Brewer JA (2019) Quitting starts in the brain: A randomized controlled trial of app-based mindfulness shows decreases in neural responses to smoking cues that predict reductions in smoking. Neuropsychopharmacology.44(9): 1631-1638.

McCarthy, JM, Dumais KM, Zegal M, Pizzagalli, DA, Olson DP, Moran LV, Janes AC (2019) Sex differences in tobacco smokers: Executive control network and frontostriatal connectivity. Drug and Alcohol Dependence. 195: 59 – 65.


Janes AC, Zegel M, Ohashi K, Betts J, Molokotos E, Olson D, Moran L, Pizzagalli DA. (2018) Nicotine normalizes cortico-striatal connectivity in non-smoking individuals with major depressive disorder. Neuropsychopharmacology. 43: 2445-2451.

Moran LV, Stoeckel LE, Wang K, Caine CE, Villafuerte R, Calderon V, Baker JT, Ongur D, Janes AC, Evins AE, Pizzagalli DA. (2018) Nicotine-induced activation of caudate and anterior cingulate cortex in response to errors in schizophrenia. Psychopharmacology. 235: 789-802.

Janes AC, Gilman JM, Frederick BB, Radoman M, Pachas G, Fava M, Evins AE. (2018) Salience network coupling is linked to both tobacco smoking and symptoms of attention deficit hyperactivity disorder (ADHD). Drug and Alcohol Dependence. 182: 93-97.

Moran LV, Betts JM, Ongur D, Janes AC. (2018) Neural responses to smoking cues in schizophrenia. Schizophrenia Bulletin. 44: 525-534.

Dumais KM, Chernyak S, Nickerson LD, Janes AC. (2018) Sex differences in default mode and dorsal attention network engagement. PLOS ONE 13(6): e0199049.

Moran LV, Stoeckel LE, Wang K, Caine CE, Villafuerte R, Calderon V, Baker JT. Ongur, D, Janes AC, Pizzagalli DA, Evins AE. (2017) Nicotine increases activation to anticipatory valence cues in anterior insula and striatum. Nicotine and Tobacco Research


McCarthy J, Zuo C, Shepherd JM, Dias, N, Lukas SE, Janes AC. (2017) Reduced interhemispheric executive control network coupling during early cocaine abstinence. Drug and Alcohol Dependence. 181: 1-4.

Dumais KM, Franklin TR, Jagannathanm K, Hager N, Gawrysiak M, Betts J, Farmer S, Guthier E, Pater H, Janes AC*, Wetherill RR. (2017) Multi-site exploration of sex differences in brain reactivity to smoking cues: Consensus across sites and methodologies. Drug and Alcohol Dependence. 178: 469-476. *Co-last author

Janes AC, Gilman JM, Radoman M, Pachas G, Fava M, Evins AE. (2017) Revisiting the role of the insula and smoking cue-reactivity in relapse: A replication and extension of neuroimaging findings. Drug and Alcohol Dependence. 179: 8-12.

Peechatka AL, Janes AC. (2017) Association between reward reactivity and drug use severity is substance dependent: Preliminary evidence from the Human Connectome Project. Nicotine and Tobacco Research. 19: 710-715.


Janes AC, Betts J, Jensen JE, Lukas SE. (2016) Dorsal anterior cingulate glutamate is associated with engagement of the default mode network during exposure to smoking cues. Drug and Alcohol Dependence. 167: 75-81.

Copersino ML, Price JS, Frost KH, Vitaliano GD, Frederick BdeB, Lukas SE, Weiss RD, Janes AC. (2016) Default Mode Network Functional Reorganization During Early Abstinence in Polysubstance-Using Emerging Adults Treated for Opioid Dependence. The Journal of Neuropsychiatry and Clinical Neurosciences. 28: 325-327.

Dias ND, Peechatka AL, Janes AC. (2016) Insula reactivity to negative stimuli is associated with daily cigarette use: a preliminary investigation using the human connectome database. Drug and Alcohol Dependence. 159: 277-80.

Putcha D, Ross R, Cronin-Golomb A, Janes AC*, Stern S. (2016) Salience and default mode network coupling predicts cognition in aging and Parkinson’s disease. Journal of the International Neuropsychological Society. Journal of the International Neuropsychological Society. 22: 205-215. *Co-last author


Peechatka A, Whitton AE, Farmer S, Pizzagalli DA, Janes AC. (2015) Cigarette craving is associated with blunted reward processing in nicotine-dependent smokers. Drug and Alcohol Dependence. 155: 202-207.

Tong Y, Hocke LM, Fan X, Janes AC, Frederick BB. (2015) Can apparent resting state connectivity arise from systemic fluctuations? Frontiers in Human Neuroscience. 9: 285.

Kaufman MJ, Janes AC, Hudson JI, Brennan BP, Kanayama G, Kerrigan AR, Jensen JE, Pope HG. (2015) Brain and Cognition abnormalities in long-term anabolic-androgenic steroid users. Drug and Alcohol Dependence. 152: 47-56.

Janes AC, Pedrelli P, Whitton AE, Pechtel P, Douglas S, Martinson MA, Huz I, Fava M, Pizzagalli, Evins AE. (2015) Reward responsiveness varies by smoking status in women with a history of major depressive disorder. Neuropsychopharmacology. 40: 1940-1946.

Putcha D, Ross RS, Cronin-Golomb A, Janes AC*, Stern CE. (2015) Altered intrinsic functional coupling between core neurocognitive networks in Parkinson’s disease. NeuroImage: Clinical.  7: 449-455. *Co-last author

Janes AC, Farmer S, Peechatka A, Blaise deB Frederick, Lukas SE. (2015) Insula-dorsal anterior cingulate cortex coupling is associated with enhanced brain reactivity to smoking cues. Neuropsychopharmacology. 40: 156-158.

Janes AC, Ross RS, Farmer S, Frederick BB, Nickerson L, Lukas SE, Stern CE. (2015) Memory retrieval of smoking-related images induce greater insula activation as revealed by an fMRI based delayed matching to sample task. Addiction Biology. 20: 349-356.

Janes AC, Park MT, Farmer S, Chakravarty MM. (2015) Striatal morphology is associated with tobacco cigarette craving. Neuropsychopharmacology. 40: 406-411.


Janes AC, Farmer S, Frederick BB, Nickerson LD, Lukas SE. (2014) An increase in tobacco craving is associated with enhanced medial prefrontal cortex network coupling. Plos One. 9: e88228.


Janes AC, Jensen JE, Farmer SL, Frederick BB, Pizzagalli DA, Lukas SE. (2013) GABA levels in dorsal anterior cingulate cortex associated with difficulty ignoring smoking-related cues in tobacco-dependent volunteers. Neuropsychopharmacology. 38: 1113-1120.

Kaufman MJ, Janes AC, Frederick BB, Brimson-Theberge M, Tong Y, McWilliams SB, Bear A, Gillis TE, Schrode KM, Renshaw PF, Negus SS. (2013) A method for conducting functional MRI studies in alert nonhuman primates: initial results with opioid agonists in male cynomolgus monkeys. Experimental and Clinical Psychopharmacology. 21: 323-331.

Ogata N, Gillis TE, Liu X, Cunningham SM, Lowen SB, Adams B, Sutherland-Smith J, Mintzopoulos, Janes AC, Dodman NH, Kaufman MJ. (2013) Brain Structural Abnormalities in Doberman Pinschers with Canine Compulsive Disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 45: 1-6.


Gillis TE, Janes AC, Kaufman MJ. (2012) Positive reinforcement training in squirrel monkeys using clicker training. American Journal of Primatology. 74: 712-720.

Janes AC, Nickerson L, Frederick BB, Kaufman MJ. (2012) Prefrontal and limbic resting state brain network functional connectivity differs between nicotine-dependent smokers and non-smoking controls. Drug and Alcohol Dependence. 125: 252-259.

Janes AC, Smoller JW, David SP, Frederick BB. Haddad S, Basu A, Fava M, Evins AE, Kaufman MJ. (2012) Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women. Drug and Alcohol Dependence. 120: 7-13.


Mashhoon Y, Janes AC, Jensen JE, Prescot AP, Pachas G, Renshaw PF, Fava M, Evins AE, Kaufman MJ. (2011) Anterior cingulate proton spectroscopy glutamate levels differ as a function of smoking cessation outcome. Progress in Neuropsychopharmacology and Biological Psychiatry. 35: 1709-1713.

Evins AE, Pachas G, Mischoulon D, Urbanoski K, Carlini S, Sousa J, Bentley K, Rigotti NA, Nino-Gomez J, Loebl T, Janes AC, Kaufman MJ, Fava, M. (2011) A double-blind, placebo-controlled trial of the NMDA glycine site antagonist, GW468816, for prevention of relapse to smoking in females.  Journal of Clinical Psychopharmacology. 31: 597-602.


Janes AC, Pizzagalli DA, Richardt S, Frederick BB, Holmes AJ, Sousa JA, Fava M, Evins AE, Kaufman MJ. (2010) Neural substrates of attentional bias for smoking-related cues: An fMRI study. Neuropsychopharmacology. 35: 2339-2345.

Janes AC, Pizzagalli DA, Richardt S, Frederick BB, Chuzi S, Pachas G, Culhane MA, Holmes AJ, Fava M, Evins AE, Kaufman MJ. (2010) Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence. Biological Psychiatry. 67: 722-729.

Wells AM, Janes AC, Liu X, Deschepper CF, Kaufman MJ, Kantak KM. (2010) Medial temporal lobe functioning and structure in the spontaneously hypertensive rat: Comparison with Wistar-Kyoto normotensive and Wistar-Kyoto hypertensive control strains. Hippocampus. 20: 787-797.


Janes AC, Frederick BB, Richardt S, Burbridge C, Merlo-Pich E, Renshaw PF, Evins AE, Fava M, Kaufman MJ. (2009) Brain fMRI reactivity to smoking-related images before and during extended smoking abstinence. Experimental and Clinical Psychopharmacology. 17: 365-373.

Kantak KM, Mashhoon Y, Silverman DN, Janes AC, Goodrich CM. (2009) Role of the orbitofrontal cortex and dorsal striatum in regulating the dose-related effects of self-administered cocaine. Behavioral Brain Research. 201: 128-136.

Janes AC, Kantak KM, Cherry JA. (2009) The involvement of type 4 phosphodiesterases in cocaine-induced sensitization and subsequent pERK expression in the mouse nucleus accumbens. Psychopharmacology. 206: 177-185.


Kang N, Janes A, Baum M, Cherry J. (2006) Sex difference in Fos induced by male urine in medial amygdala-projecting accessory olfactory bulb mitral cells of mice. Neuroscience Letters. 398: 59-62.


Tomie A, Di Poce J, Aguado A, Janes A, Benjamin D, Pohorecky L. (2003) Effects of autoshaping procedures on 3H-8-OH-DPAT- labeled 5-HT1a binding and 125I-LSD-labeled 5-HT2a binding in rat brain. Brain Research. 975: 167-178.